Twenty-something and aimless, Joey Vitello still lives at home with his colorful Italian-American family when he is reunited with a childhood schoolmate, Mary O'Callahan. Once mocked as "Scary Mary, " this ugly duckling has blossomed into an irresistible beauty. She's returned to the old neighborhood after an intense bout with cancer. When Joey learns her cure was the result of a miracle, friendship turns to romance as she educates him on the crossroads...

When Tom learns he has terminal brain cancer, he decides to find a replacement husband for his wife and a father for his daughter before it's too late. Unbeknownst to his wife Valentine, Tom sets up an on-line dating profile for her, but quickly realizes he doesn't know much about her anymore. So, in order to find a perfect match, Tom endeavors to get to know her again, and during that time, remembers why he fell in love with her all those years...

When promising high school basketball player Eric "Hoovey" Elliott collapses on the court, doctors discover a life-threatening brain tumor. Hoovey will survive the high-risk surgery, but at what cost? Can he relearn to walk, read, even to see clearly? The road is long, and meanwhile overwhelming medical bills threaten to undo everything his parents, Jeff and Ruth, have taken a lifetime to build.

"In the middle of an Australian summer, we meet three sisters. Nina is widowed with two young children. Anna is an aspiring actress unhappily married to a filmmaker. Christine is a med student who has yet to fully come to terms with her sexuality. When their mother Susan's breast cancer returns, the family is faced with the reality of their last Christmas together. As each daughter confronts personal change and growth, Susan guides them by revealing...

After receiving a terminal cancer diagnosis, Carnegie Mellon Professor Randy Pausch delivers a lecture on the hard facts that one encounters when realizing his mortality.

Takada is an aging Japanese fisherman who has been estranged from his son for many years. When the son is diagnosed with terminal cancer his daughter-in-law, Rie, summons him to the hospital. When his son refuses to see him, Rie gives him a videotape about the work his son was doing on a documentary film in a remote region of China's Yunnan province. Still troubled by the relationship, Takada decides to go to China and complete his son's work in part...

A police detective suffering from cancer makes a deal with an informant to get killed in the line of duty, so his family can receive the hefty death benefits from the department.

In the final episodes, Emmy winners Bryan Cranston and Aaron Paul bring the saga of Breaking Bad to a bloody conclusion in their roles as meth kingpin Walter White and his guilt-ridden partner Jesse Pinkman. As each tries to get clear of the wreckage they left behind in the meth world, DEA agent Hank Schrader's obsessive pursuit of 'Heisenberg' gains steam, leading up to a shattering finale that will leave no one in Walt's world unscathed.